Laboratory and Cryobiological Cryogenic Liquid Uses

Laboratory equipment and sensors, environmental chambers, and the storage / preservation of biological samples are frequent uses for cryogenic liquids. Liquid cryogens can be used to rapidly reduce sample temperatures, maintain samples at very cold conditions, and create an environment to test products. Liquid nitrogen (LN2), for its versatility, and liquid helium (LHe), for its ultra-cold characteristics, make them popular cryogenic liquids used in the laboratory.

Medical facilities, both research and commercial, commonly use cryogenic liquids for test equipment and for the storage and shipment of biological samples. Magnetic Resonance Imaging (MRI) units use liquid helium to cool their ultra-powerful magnets. Liquid nitrogen is most often used in the storage, handling and shipment of biological samples, although some MRI units also utilize liquid nitrogen. Another application that many people are familiar with if they have visited a dermatologist, is the removal of warts or diseased tissue with liquid nitrogen using a swab or cryospray device.

The major cryobiology uses for Technifab products involve the cryopreservation of cells and tissues, cryosurgery, and lyophilization. Cryogenic liquids have advantages over mechanical freezers due to their speed and ability to limit the sharp ice crystals in tissue and cells that can form with other methods.


Technifab’s vacuum jacketed products are ideal in a laboratory or cryobiological setting where reduced condensation, frost, and non-corrosiveness is valued. The added efficiency, quick cryogen delivery, performance and cost savings are additional benefits that make our vacuum jacketed products even more valuable in laboratory and cryobiological settings.

Vacuum jacketed pipe and vacuum jacketed transfer hoses are frequently used for delivery of liquid nitrogen and liquid helium. Technifab’s Techniguard line of rigid and bendable vacuum insulated pipe and our Techflex hoses allow frost-free transfer of liquid cryogens that look as good as they perform. Many Original Equipment Manufacturers (OEMs) use Techniguard vacuum jacketed pipe or Techflex transfer hoses in their laboratory or equipment.

Phase separators and valves may be used in the system to make sure a more consistent and better quality liquid cryogen is being delivered where and when it is needed.

For transferring cryogenic liquids transfer hoses may have ‘stingers’ on one end to take liquid to or from a dewar. Charging MRI units or delivery to storage dewars, especially utilizing liquid helium makes this a popular use. Helium’s cold temperatures and high cost have made Technifab’s Liquid Helium Equipment a popular choice. Our hoses have been proven superior in performance in independent laboratory tests, resulting in lower liquid helium losses than competitors.

We’ve also released special Techniguard vacuum insulated pipe that is designed for rapid delivery of liquid nitrogen or other cryogens to the use point. Techniguard R50T and R65T pipe is ideal for cryobiological settings or for freezers which have intermittent liquid nitrogen use.

Our line of cryogenic dewars are often used in locations where small quantities of cryogens are needed or that may not have a cryogen delivery system. We also offer a biological dewar that is designed for holding biological samples. We provide dewars manufactured with the same quality and customer service that we provide with our other products. We even offer dewars online for faster delivery of these high performance products.

Getting from a tank or cryogen delivery point to use point often requires a cryogenic manifold or switching station. We can provide a customized vacuum insulated manifold with the number of inlets, outlets, valves, bayonets or connection points that you need. If you are supplying your system from dewars or VGL tanks, you may want to look at our vacuum jacketed switching station – the only frost-free, drip free dewar switching station on the market today!